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Marmaduke (2010)

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Synopsis: Marmaduke, the world’s most lovable Great Dane, leaps from comic strip fame (appearing in 600 newspapers in over 20 countries) to big screen stardom in this family comedy event. A suburban family moves to a new neighborhood in Orange County, California with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way. But it’s not all living large for the Duke, who finds that fitting in with his new four-legged friends – and a potential romantic interest – isn’t always easy for a super-sized teenage dog. Owen Wilson gives the beloved Great Dane his voice in the film, which also features the voices of Fergie, George Lopez, Emma Stone and Kiefer Sutherland.
Director: Tom Dey
Writers: Tim Rasmussen, Vince Di Meglio
Stars: Owen Wilson, Judy Greer, Lee Pace
Sources: IMDB, Wikipedia